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“Various animal research have proven the hepatotoxic (and presumably deadly) potential of GTE,” he says. As soon as patients begin one of the medications, it’s not clear how long they need to stay on – a question that deserves additional analysis, Rawson says. Rawson warns that rehab may increase the chance of an overdose, as a result of your body’s tolerance to opioids is lower after you withdraw from them. Rawson and others point to two medication in particular which will help break your addiction: buprenorphine and methadone. In addition they reduce your possibilities of an overdose, Rawson says. There is a few unwarranted stigma connected to these drugs, together with a belief that “you’re just exchanging one addiction for another,” Kan says. Kan and different addiction specialists usually don’t encourage medicine therapy alone, no matter how lengthy you keep on it.